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Table 2 Genes differentially expressed in H. influenzae Eagan at pH 8.0 compared to pH 6.8

From: There is a specific response to pH by isolates of Haemophilus influenzae and this has a direct influence on biofilm formation

Genes up-regulated at pH 8.0 compared to 6.8
Metabolic genes
Gene Log 2 fold p -values FDR Comment
HI1010 2.21 5.12×10-10 1.02×10-7 6-phosphogluconate dehydrogenase
HI1011 2.20 6.83×10-10 1.22x10-7 Similar to YgbK
HI1012 2.04 3.06×10-8 3.64x10-6 Sugar isomerase
HI1013 1.88 3.04×10-7 2.86×10-5 Hydroxypyruvate isomerase
HI1014 1.52 2.33×10-5 1.54×10-3 Sugar epimerase
HI1015 1.12 1.18×10-3 4.70×10-2 GntP family, gluconate:H+ symporter
HI0091 1.74 5.98×10-7 5.33×10-5 Hypothetical protein; homologous to GlxK, glycerate kinase
HI0092 2.14 1.49×10-9 2.41×10-7 GntP family, gluconate:H+ symporter
Iron uptake genes
Gene Log 2 fold p -value FDR Comment
HI0995 1.53 1.72×10-5 1.23×10-3 OMP, iron-binding
hitA 2.21 1.69×10-10 3.77×10-8 Iron uptake
hxuB 1.65 1.54×10-6 1.25×10-4 Hemopexin utilization protein
hxuC 1.70 8.04×10-7 6.83×10-5 TonB-dependent heme receptor
Genes of unknown function
Gene Log 2 fold p -value FDR Comment
HI1427 1.54 6.87×10-6 5.33×10-4 Hypothetical protein
Genes down-regulated at pH 8.0 compared to 6.8
Gene Log 2 fold p -value FDR Comment
HI1349 -2.31 5.58×10-11 1.42×10-8 Ferritin
HI1385 -1.55 2.27×10-5 1.54×10-3 FtnB; non-heme ferritin