Figure 3From: Perturbation of copper homeostasis is instrumental in early developmental arrest of intraerythrocytic Plasmodium falciparum Growth of P. falciparum co-cultured with PfRBCs and RBCs that were pretreated separately with TTM. Synchronized PfRBCs at the ring stage and RBCs were treated with graded concentrations of TTM for 0.5Â h or 2.5Â h at room temperature. After washing, both treated PfRBCs and RBCs were mixed (pretreated PfRBCs plus non-treated RBCs (a) or non-treated PfRBCs plus pretreated RBCs (b)) at a ratio of more than 10 times RBCs to PfRBCs and cultured in GFSRPMI for 95Â h; (*) indicates a significant difference versus no treatment with TTM (0).Back to article page