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Table 1 Effects of microbial antigens on lymphocyte growth with or without IL-6 and TGF β1

From: Role of IL-17A and IL-10 in the antigen induced inflammation model by Mycoplasma pneumoniae

Antigen

IL-6(-), TGF-β1(-)a

IL-6(+), TGF-β1(+)a

0 μg/ml

50 μg/ml

0 μg/ml

1 μg/ml

5 μg/ml

10 μg/ml

50 μg/ml

M. pneumoniae M129

 

229.6±19.1b

 

81.9±5.8

101.5±10.9

134.7±15.6c

147.8±6.3c

S. pneumoniae ATCC 33400

 

18.4±1.2b

 

110.1±6.3

100.9±12.9

66.8±5.2c

22.3±2.4c

K. pneumonia ATCC 13883

111.7±13.0

6.8±4.2b

100.0±8.1

109.2±4.1c

44.3±1.2c

27.3±1.6c

6.1±0.7c

LPS from E. coli 0127: B8

 

128.8± 6.1b

 

86.5±2.7c

89.4±8.1

81.2±5.0c

56.5±7.0c

Zymosan A from S. cerevisiae

 

197.9±10.2b

 

104.5±10.1

114.8±9.6c

124.9±4.0c

159.1±5.4

  1. aRelative ratio (%) of viable lymphocyte count with or without IL-6 (20 ng/ml) and TGF-β1 (2 ng/ml) stimulated with M. pneumoniae and other antigens. Relative ratio is the mean ± standard deviation (four or five samples per group) of the number of viable lymphocytes at day 4.
  2. bSignificantly different (p < 0.05) from value for cytokine (−), antigen 0 μg/ml by Student’s t-test.
  3. cSignificantly different (p < 0.05) from value for 20 ng/ml of IL-6 and 2 ng/ml of TGF-β1 (+), antigen 0 μg/ml by Dunnett multiple comparison statistical test.
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BMC Microbiology

ISSN: 1471-2180

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