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Table 4 Frequencies of beta-lactam resistance and clinical characteristics in study groups and in the original population a

From: Multilocus sequence typing and ftsI sequencing: a powerful tool for surveillance of penicillin-binding protein 3-mediated beta-lactam resistance in nontypeable Haemophilus influenzae

   rPBP3c Bla d Proportions (%) of isolates and patients
Groups of isolatesb n n % n % Anatomical sites Age groups Hospitalizede
       Eye Ear Respiratory 0-3 ≥50  
Resistant group 177 116 66 16 9 28 10 58 44 24 33
Susceptible group 19 0 0 0 0 21 32 42 68 5 11
Remaining isolates 599 0f 0f 60g 10g 19 15 63 41 22 23
Original population 795h 116 15 76 10 21 14 62 43 22 25
  1. aNORM 2007 surveillance population [33], consisting of consecutive routine isolates from patients with eye, ear and respiratory tract infections.
  2. bSee text and Figure 1 for definition of the study groups (Resistant group and Susceptible group).
  3. cPBP3-mediated resistance (see Table 1).
  4. dBeta-lactamase positive.
  5. eProportions of patients hospitalized at the time of sampling.
  6. fAssuming that all rPBP3 isolates were selected for the Resistant group.
  7. gAs reported by the primary laboratories.
  8. hThirteen isolates were selected for the Resistant group but excluded for various reasons (see Figure 1).