|
Virulence factors
|
Pathotype
|
|---|
| |
Non-pathogenic E. coli*
|
Diarrhea-associated E. coli**
|
ExPEC***
|
|---|
| |
n = 399 (%)
|
n = 179 (%)
|
n = 603 (%)
|
|---|
|
Aggregative adherence plasmid
|
pCVD432
|
-
|
13 (7.3)
|
-
|
|
Invasive associated locus
|
ial
|
-
|
44 (24.6)
|
-
|
|
Heat-stable enterotoxin
|
st
|
-
|
8 (4.5)
|
-
|
|
Heat-labile enterotoxin
|
lt
|
-
|
7 (3.9)
|
-
|
|
Intimin
|
eaeA
|
-
|
26 (14.5)
|
-
|
|
Bundle-forming fimbriae
|
bfpA
|
-
|
1 (0.6)
|
-
|
|
Invasion plasmid H
|
ipaH
|
-
|
19 (10.6)
|
-
|
|
Aerobactin synthesis
|
aer
|
-
|
68 (38.0)
|
342 (56.7)
|
|
Fimbriae type 1
|
fimA
|
336 (84.2)
|
149 (83.2)
|
553 (91.7)
|
|
α-hemolysin
|
α-hly
|
-
|
3 (1.7)
|
88 (14.6)
|
|
Afimbrial adhesin
|
afaI
|
-
|
78 (43.6)
|
-
|
|
Aerobactin synthesis
|
iucC
|
-
|
80 (44.7)
|
396 (65.7)
|
|
Cytotoxic necrotizing factor
|
cnf1
|
-
|
1 (0.6)
|
43 (7.1)
|
|
S-fimbriae
|
sfa
|
-
|
6 (3.4)
|
227 (37.6)
|
|
P-fimbriae
|
pap
|
-
|
19 (10.6)
|
201 (33.3)
|
|
Shiga-toxin 1
|
stx1
|
-
|
-
|
-
|
|
Shiga-toxin 2
|
stx2
|
-
|
-
|
-
|
|
Enterohemolysin
|
ehly
|
-
|
9 (5.0)
|
-
|
- *E. coli strains with no detected genes for virulence factors or those possessing only gene for fimbriae type I (fimA gene).
- **EAggEC - pCVD432 (aggregative adherence plasmid); ETEC - lt/st (heat-labile and heat-stable enterotoxin); EIEC - ial/ipaH (invasion associated locus/invasion plasmid H); EPEC – bfpA/eaeA (bundle-forming fimbriae/intimin); EHEC (stx1/stx2/ehly); DAEC – afaI (afimbrial adhesin I).
- ***E. coli strains which contain different virulence factors (except those that are typical for previously described diarrhea-associated E. coli) typical for extraintestinal E. coli strains (α-hemolysin, P-fimbriae, S-fimbriae, cytotoxic necrosis factor, aerobactin synthesis).
