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Table 4 Virulence of selected mutant strains

From: Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella entericaserovar Typhimurium

Strains Description 1CI ± SD
JTR.452 yajD 1.2 ± 0.3
JTR.481 wraB & ychN 1.9 ± 0.7*
JTR.482 wraB & osmC 0.7 ± 0.2*
JTR.490 ychN & dcoC 1.4 ± 0.9
JTR.498 cbpA & osmC 1.4 ± 0.3
JTR.499 cbpA & dcoC 0.4 ± 0.1*
  1. 1The competitive index (CI) and its standard deviation (SD) were calculated by dividing the proportion of mutant colonies in the spleen by the proportion of mutant colonies in the inoculum used to infect the mice, as previously reported [75].
  2. *The CI is significantly different from 1, by one-sample t-test, indicating a significant change in the ability of the mutant strain to reside or propagate in mice with respect to the wild type.