Strains | Description | 1CI ± SD |
---|
JTR.452 |
yajD
| 1.2 ± 0.3 |
JTR.481 |
wraB & ychN
| 1.9 ± 0.7* |
JTR.482 |
wraB & osmC
| 0.7 ± 0.2* |
JTR.490 |
ychN & dcoC
| 1.4 ± 0.9 |
JTR.498 |
cbpA & osmC
| 1.4 ± 0.3 |
JTR.499 |
cbpA & dcoC
| 0.4 ± 0.1* |
- 1The competitive index (CI) and its standard deviation (SD) were calculated by dividing the proportion of mutant colonies in the spleen by the proportion of mutant colonies in the inoculum used to infect the mice, as previously reported [75].
- *The CI is significantly different from 1, by one-sample t-test, indicating a significant change in the ability of the mutant strain to reside or propagate in mice with respect to the wild type.