C. albicansgrowth, transition, biofilm formation, and gene expression modulation by antimicrobial decapeptide KSL-W

Table 2 Gene expression (6 h) under non-hyphae inducing culture conditions

Gene	Untreated *C. albicans*	Amphotericin B		KSL-W 25 μg/ml		KSL-W 100 μg/ml
Gene	Fold change¹	Fold change¹	p-value²	Fold change¹	p-value²	Fold change¹	p-value²
SAP2	0.99	0.57	0.001	0.24	<0.001	0.11	<0.001
SAP4	0.96	0.19	<0.001	0.29	<0.001	0.14	<0.001
SAP5	1.00	0.08	<0.001	0.16	<0.001	0.06	<0.001
SAP6	1.00	0.05	<0.001	0.14	<0.001	0.04	<0.001
EAP1	1.00	4.91	0.028	0.4	<0.001	0.29	<0.001
HWP1	1.00	0.01	<0.001	0.6	0.032	0.02	<0.001

¹Fold change was calculated by PCR product of the gene of interest/the PCR product of ACT1 (the house keeping gene), and normalized to the negative control of untreated C. albicans where the expression was considered equal to 1.
²P-values were obtained after comparison of test to negative control (untreated C. albicans).

ISSN: 1471-2180