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Table 3 Growth kinetics in cultures co-expressing the mazF6 toxin with cognate and non-cognate antitoxins

From: MazF6 toxin of Mycobacterium tuberculosis demonstrates antitoxin specificity and is coupled to regulation of cell growth by a Soj-like protein

  MazE % Reduction in growth
MazF6 expressed with non-cognate antitoxins 1 17
2 30
3 11
4 17
5 19
7 33
9 24
MazF6 alone - 46
MazE6 alone - 5
MazF6 6 4
  1. Growth reduction associated with overexpression of the mazF6 toxin can be rescued by co-expression of its cognate antitoxin. Full rescue of the growth defect is not observed when co-expressed with non-cognate antitoxins.