Heatmap of the profile for 15 RE recognition sites on MLS DNA sequences for 110 H. pylori strains. Higher and lower frequencies of the cognate recognition sites are represented by red and blue, respectively. The upper tree showed three main strainclusters: A) Includes hspAmerind (N=25), hspEAsia (N=5), and hpEurope (N=7) strains; B) Mostly hpEurope (N=21), but also hspEAsia (N=6), and hpAfrica1 (N=2) strains; and C) hpAfrica1 (N=23), and hpEurope (N=20) strains. The hpEurope strains studied were mostly recovered from Mestizo hosts. The phylogeny on the left shows two enzyme clusters, that correlate with the A, B and C cluster-strains.