Non-parametric multidimensional scaling (NMDS) based on the RMS profile for 15 restriction endonucleases in H. pylori DNA sequences. NMDS is a visual representation of the most parsimonious distances, in terms of similarities and disparities, among the sequences. It provides a lower k-dimensional space, based on each restriction profile, which is the combination of the number of restriction sites for each of the 15 enzymes analyzed per sequence. Panel A: Analysis of 110 multilocus sequences. The restriction profile is distinct among haplotypes with the sequences clustering into groups, except for hpEurope that seems to have a more mixed restriction profile, with similarities with some hpAmerind and most hpAfrica1 strains. Panel B: Analysis of seven whole genome sequences. The restriction profile of the whole genome sequences is distinct among the H. pylori sub-groups, with hpEurope, hspAmerind, and hpAfrica1 clustering separated of each other.