Skip to main content

Table 3 IC 50 values (μM) of the naphthoquinones on intracellular amastigotes of T. cruzi

From: Trypanosoma cruzi mitochondrial swelling and membrane potential collapse as primary evidence of the mode of action of naphthoquinone analogues

Cpd

HMC

Macrophages

NQ1

2.81 ± 0.43a,b

3.65 ± 0.71

NQ8

1.53 ± 0.11

1.49 ± 0.01

NQ9

2.48 ± 0.39

1.63 ± 0.18

NQ12

9.83 ± 2.64

2.51 ± 0.71

  1. aThe IC50 was calculated for the endocytic index (number of parasites/100 host cells) after two days of treatment.
  2. bMean ± standard deviation of at least three independent experiments.
Back to article page

BMC Microbiology

ISSN: 1471-2180

Contact us