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Table 1 Number of isolates in each group (total of 120) exhibiting each of the traits measured

From: Sub-inhibitory concentrations of some antibiotics can drive diversification of Pseudomonas aeruginosa populations in artificial sputum medium

  Colony morphology Virulence Mutations Outside normal range of antimicrobials susceptibility
Culture Green non-mucoid Straw non-mucoid Pyocyanin Hypermutability Ceftazidime Ciprofloxacin Tobramycin Meropenem Colistin Tazobactam/piperacillin
ASM 120 0 117 0 3 0 19 0 2 8
ASM + CAZ 110 10 92 0 16 19 20 18 10 11
ASM + CT 113 7 84 0 17 37 29 15 7 9
ASM + AZT 120 0 120 0 0 16 34 0 4 4
ASM + MEM 120 0 118 0 1 8 4 0 0 1
ASM + TOBI 118 2 119 0 1 24 69 3 22 1
LB (18 hours) 120 0 120 1 0 0 0 0 0 0
  1. Isolates that were characterized as being outside the normal range of antimicrobial susceptibility typically observed in LESB58, included isolates that had either an increased or reduced susceptibility to the antibiotic under test. ASM = Artificial Sputum Medium, LB = Luria Bertani, CAZ = Ceftazidime, CT = Colistin, AZT = Azithromycin, MEM = Meropenem and TOBI = Tobramycin.