A Method for generating marker-less gene deletions in multidrug-resistant Acinetobacter baumannii

BMC Microbiology

Table 1 Antimicrobial susceptibility of MDR A. baumannii DB, R2 and pump deletion mutants

Antibiotic	DB	DB∆adeFGH	DB∆adeIJK	DB∆adeFGH∆adeIJK	R2	R2∆adeFGH	R2∆adeIJK	R2∆adeFGH∆adeIJK
Nalidixic acid	512	512	128	128	1024	1024	256	256
Ciprofloxacin	64	64	64	64	128	128	128	128
Chloramphenicol	64	64	16	16	128	128	32	32
Tetracycline	512	512	128	128	512	512	128	128
Minocycline	2	2	0.25	0.25	2	2	0.5	0.5
Tigecycline	1	1	0.25	0.25	1	1	0.25	0.25
Meropenem	128	128	128	128	64	64	64	64
Imipenem	32	32	32	32	64	64	64	64
Piperacillin	512	512	512	512	256	256	256	256
Oxacillin	> 1024	>1024	> 1024	>1024	1024	1024	1024	1024
Ceftazidime	256	128	256	256	256	128	512	512
Erythromycin	512	512	512	512	512	512	512	512
Clindamycin	128	128	16	16	128	128	16	16
Trimethoprim	128	128	16	16	128	128	16	16
Gentamicin	>1024	>1024	>1024	>1024	>1024	>1024	>1024	>1024
Kanamycin	>1024	>1024	>1024	>1024	>1024	>1024	>1024	>1024

ISSN: 1471-2180