Protein level identification of the Listeria monocytogenes Sigma H, Sigma L, and Sigma C regulons

BMC Microbiology

Table 4 Proteins found to be differentially regulated by at least two of the three alternative sigma factors studied here

	Regulation by^b			Regulation by σ^Bc	Differential levels in comparison between parent and ΔBCHL
Protein^a	σ^H	σ^L	σ^C	Regulation by σ^Bc
Lmo0027	+	-	NDR	NDR	-
Lmo0096 (MptA)	+	+	+	NDR	+
Lmo0319 (BglA)	+	-	NDR	NDR	-
Lmo1877 (Fhs)	-	-	NDR	NDR	-
Lmo2006 (AlsS)	+	+	NDR	NDR	+
Lmo2094	-	-	-	NDR	-
Lmo2097	-	-	NDR	NDR	-
Lmo2098	-	-	NDR	NDR	NDR

^aWhere available, protein name is shown in parenthesis.
^bProteins that were identified here as positively (+) or negatively (−) regulated (absolute FC > 1.5; p < 0.05) by a given σ factor are shown; NDR (“not differentially regulated”) indicates that a protein was not found to be differentially regulated between strains with and without a given alternative σ factor.
^cData for proteins differentially regulated by σ^B were obtained from Mujahid et al. [23]; this study compared protein levels between the 10403S parent strain and an isogenic ΔsigB strain.

ISSN: 1471-2180