Overview of mutations detected in all strains analyzed in a) kat G, b) rpo B, c) rps L, d) emb B and e) pnc A. The height of the columns represent the number of strains analyzed. On the x-axis the different mutated codons are shown. The white areas of the columns represent the fraction of susceptible strains, whereas the black areas correspond to the number of resistant strains. Abbreviations: WT, wild type; singletons, various codons that are affected in one strain only.