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Figure 4 | BMC Microbiology

Figure 4

From: Lactobacillus acidophilus ameliorates H. pylori-induced gastric inflammation by inactivating the Smad7 and NFκB pathways

Figure 4

Pre-treatment of L. acidophilus significantly reduced JAK1 (MOI 1-100), STAT1 (MOI 10-100), and SMAD7, and subsequent NFκB production after (A) H. pylori and (B) IFN-γ treatment. N, AGS cell only; P, H. pylori, MOI = 100 (A, black column) and 100 ng/ml IFN-γ (B, black column) treatment for 0.5 hour; MOI 1, 10, and 100 meant pre-treatment with L. acidophilus 1 × 106, 1 × 107, 1 × 108 c.f.u. for 8 hours, respectively, followed by H. pylori treatment for 0.5 hour (* P < 0.05; ** P < 0.01).

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