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Table 2 Major seroreactive proteins of C. burnetii on microarray probed with Q fever patient sera

From: Potential serodiagnostic markers for Q fever identified in Coxiella burnetiiby immunoproteomic and protein microarray approaches

  Fluorescence intensity Sensitivitya
Protein Normal (n = 25) Acute early (n = 25) Acute late (n = 25) Convalescent (n = 6) Acute early Acute late Convalescent
GroEL 114 ± 84 1548 ± 1996 3915 ± 3462 642 ± 382 84% 88% 83%
YbgF 104 ± 83 752 ± 1308 1517 ± 1946 1176 ± 1061 44% 72% 67%
RplL 85 ± 88 277 ± 396 949 ± 1174 185 ± 119 20% 68% 17%
Mip 137 ± 78 324 ± 233 611 ± 669 237 ± 157 44% 60% 17%
Com1 70 ± 84 120 ± 326 461 ± 525 253 ± 176 12% 52% 50%
OmpH 141 ± 95 210 ± 195 676 ± 1192 398 ± 540 20% 48% 17%
DnaK 95 ± 91 143 ± 122 371 ± 480 165 ± 105 16% 48% 17%
  1. aSensitivity was calculated as the percentage (the number of microarray-positive sera divided by the number of sera of patients with Q fever)