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Table 3 Occurrence of preS deletion mutants in serial samples during ADV treatment

From: Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment

Patients (CH)

Start

End

 

PCR direct sequencing

PCR direct sequencing

Clone sequencing

ADV

1

N

D

aa 65–78 (peS1),

(+)

(Jan 24, 2005)

(Mar 22, 2005)

3/5 clones

 

2

N

D

aa 132–141 (preS2),

 

(Dec 15, 2004)

(Mar 21, 2005)

2/5 clones

ADV

3

N

N

-

(−)

(Dec 17, 2004)

(Feb 28, 2005)

 

4

N

N

-

  

(Jan 14, 2005)

(Jun 7, 2005)

 
  1. N, no deletion detected; D, deletion detected.
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BMC Microbiology

ISSN: 1471-2180

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