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Table 3 Occurrence of preS deletion mutants in serial samples during ADV treatment

From: Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment

Patients (CH) Start End
  PCR direct sequencing PCR direct sequencing Clone sequencing
ADV 1 N D aa 65–78 (peS1),
(+) (Jan 24, 2005) (Mar 22, 2005) 3/5 clones
  2 N D aa 132–141 (preS2),
  (Dec 15, 2004) (Mar 21, 2005) 2/5 clones
ADV 3 N N -
(−) (Dec 17, 2004) (Feb 28, 2005)
  4 N N -
   (Jan 14, 2005) (Jun 7, 2005)  
  1. N, no deletion detected; D, deletion detected.