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Figure 1 | BMC Microbiology

Figure 1

From: Yersinia pestis insecticidal-like toxin complex (Tc) family proteins: characterization of expression, subcellular localization, and potential role in infection of the flea vector

Figure 1

A) The Tc protein locus of Y. pestis contains the yitABC and yipAB insecticidal-like protein genes and the upstream regulator yitR . Alignment of the Tc locus for all sequenced Y. pestis strains is shown with differences from KIM10+ indicated. The deletions in the Y. pestis KIM6+ΔyitR and ΔyitA-yipB mutant strains used in this study are indicated. B) Domain structure of YitA and YipA. Hatch marks represent the region of YitA with similarity to the Salmonella virulence plasmid A (VRP1) protein family. The light gray area designates the region of YipA similar to the Rhs protein family. Light gray shaded hatch marks indicate the RHS repeat-associated core domain. Dark gray represents the region sharing homology to the protein tyrosine phosphatase (PTP) protein family and the PTP catalytic domain. The arrow indicates the inferred location of post-translational processing of YipA. The translational fusion junction of the full-length YitA and YipA with the mature β-lactamase is designated by shaded triangles.

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BMC Microbiology

ISSN: 1471-2180

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