Figure 1

Percent survival of mice immunized by i.p. injection with sterile PBS or 1 x 10³CFU of the gidA mutant vaccine strain, and subsequently challenged with a lethal dose (1 x 10⁵CFU) of WT STM on day 42 post-immunization. Morbidity and mortality of these animals were monitored for 30 days after challenge. Full protection was provided to immunized mice while 100% mortality was seen in the control mice.