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Table 2 Evaluation of the toxicity of the gomesin treatment

From: Therapeutic use of a cationic antimicrobial peptide from the spider Acanthoscurria gomesianain the control of experimental candidiasis

  NINF* NINF + GOM**
Leukocytes (mm3) 4637 ± 1114 4462 ± 1580
Neutrophils (mm3) 846 ± 288 1208 ± 388***
Eosinophils (mm3) 46 ± 46 135 ± 72***
Lymphocytes (mm3) 3744 ± 981 2660 ± 437***
Hemoglobin (g/dL) 13 ± 0.9 13 ± 0.5
Reticulocytes (%) 5.5 ± 0.7 9.3 ± 2.8***
Total Bilirubin (mg/dL) 0.48 ± 0.23 0.3 ± 0.1
Direct bilirubin (mg/dL) 0.35 ± 0.19 0.2 ± 0.1
Indirect bilirrubin (mg/dL) 0.13 ± 0.13 0.09 ± 0.009
Creatinine (mg/dL) 0.32 ± 0.09 0.34 ± 0.05
Gamma-GT (mg/dL) < 1 U/L < 1 U/L
  1. * Non-infected mice
  2. ** Non-infected mice treated with gomesin (GOM)
  3. *** p < 0.05