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Table 3 Approximate percentages of organisms showing ultrastructural alterations observed in two H. pylori strains after treatment with polysorbate 80, clarithromycin, metronidazole, polysorbate 80/clarithromycin and polysorbate 80/metronidazole

From: Polysorbate 80 and Helicobacter pylori: a microbiological and ultrastructural study

Parameters Controls Polysorbate 80 Clarithromycin Metronidazole Polysorbate 80/ Polysorbate 80/
          Clarithromycin Metronidazole
  CCUG 17874 C/M-R2 CCUG 17874 C/M-R2 CCUG 17874 C/M-R2 CCUG 17874 C/M-R2 CCUG 17874 C/M-R2 CCUG 17874 C/M-R2
% Altered Shape 5 3 90 60 85 50 85 5 100 95 85 80
% Granular Cytoplasm 1 3 90 70 10 40 5 5 75 60 70 65
% Altered outer membrane 1 1 75 75 20 35 20 1 70 75 70 75
% Presence of “holes” in the cytoplasm 0 0 1 0 40 2 2 1 20 1 1 15
% Detachment membrane/cytoplasm 3 1 10 2 30 2 60 2 25 2 50 10
% Presence of flagella YES YES NO YES YES YES NO YES YES YES NO NO
% Presence of vesicles - + ++ ++++ - ++ - + +/− ++++ ++ ++