Table 2 Macrolide resistance genotypes of 295 isolates of erythromycin-resistant S. pyogenes , indicating the phenotypes and emm /T types detected
Macrolide resistance genotype | No. of isolates | Phenotypea | emm/T typesa | ||
|---|---|---|---|---|---|
(%) | cMLSB | iMLSB | M | ||
erm(B) | 14 (4.7) | 14 | - | - | emm6T6 (1b), emm11T11 (5b) |
emm28T28 (6c), emm71TNT (1) | |||||
emm78T11 (1) | |||||
erm(B)/erm(A) | 1 (0.3) | 1 | - | - | emm12T12 |
erm(B)/ msr(D) | 5 (1.7) | 5 | - | - | emm11T11 (1b), emm28T28 (3) |
emm88T28 (1) | |||||
erm(B)/mef(A) | 21 (7.1) | 20 | - | 1 | emm4T4 (1), emm28T28 (18) |
emm28TNT(1), emm75T25 (1) | |||||
erm(B)/ msr(D)/mef(A) | 33 (11.2) | 8 | - | 25 | emm1T1 (1), emm2T2 (1) |
emm4T4 (14), emm6T6 (2) | |||||
emm11T11 (2b), emm12T12 (4) | |||||
emm28T28 (4), emm75T25 (4) | |||||
emm84T25 (1) | |||||
erm(B)/ msr(D)/ erm(A) | 2 (0.7) | 2 | - | - | emm11T11 (2b) |
erm(B)/ erm(A)/mef(A) | 7 (2.4) | 5 | 2 | - | emm11T11 (1b), emm28T28 (4) |
emm77T28 (1b), emm83TNT (1b) | |||||
erm(B)/ msr(D)/mef(A)/ erm(A) | 27 (9.2) | 2 | 1 | 24 | emm1T1 (1), emm4T4 (3) |
emm11T11 (1), emm12T12 (3) | |||||
emm75T25 (14),emm81TB3264(1) | |||||
emm84T25 (4) | |||||
erm(A)/mef(A) | 6 (2.0) | 1 | 1 | 4 | emm2T2 (3), emm28T28 (2) |
emm77T28 (1b) | |||||
erm(A) | 2 (0.7) | - | 2 | - | emm3T3/13 (1), emm22T12 (1) |
erm(A)/ msr(D) | 3 (1.0) | - | 2 | 1 | emm22T12 (2), emm75T25 (1) |
msr(D) | 1 (0.3) | - | - | 1 | emm3T3 (1) |
msr(D)/mef(A) | 112 (38.0) | - | - | 112 | emm1T1 (6), emm4T4 (62), |
emm6T6 (26), emm12T12 (10) | |||||
emm28T28 (1), emm75T25 (6) | |||||
emm84T25 (1) | |||||
msr(D)/mef(A)/ erm(A) | 58 (19.7) | - | - | 58 | emm1T1 (1), emm4T4 (36) |
emm12T12 (2), emm12TNT (1) | |||||
emm44T5/27/44 (1), emm75T25 (17) | |||||
None gene | 3 (1.0) | 2 | - | 1 | emm1T1 (1), emm28T28 (1) |
emm28TNT (1) | |||||
Total | 295 (100) | 60 | 8 | 227 | |