Figure 2

Relative abundance indexes and changes in protein expression levels of protein involved in glycolysis, glycogen metabolism, and pentose phosphate pathway. Relative abundance indexes (values 1 and 2), changes in protein expression ratios (value 3), and associated V _diff values (value 4) indicating confidence levels of changes in expression ratios are indicated for enzymes involved in (A) glycolysis, (B) glycogen metabolism, and (C) pentose phosphate pathway. Given the absence of genes encoding transaldolase, we propose an alternative pathway for production of xylulose-5-phosphate and ribose-5-phosphate using fructose-1,6-P aldolase and PP_i phosphofructokinase. Metabolites shown in grey are those commonly metabolized by these enzymes. G-1-P, glucose-1-phosphate; G-6-P, glucose-6-phosphate; F-1-P, fructose-1-phosphate; F-1,6-P, fructose-1,6-bisphosphate; DHA-P, dihydroxyacetone phosphate; GA-3-P, glyceraldehydes-3-phosphate; PG, phosphoglycerate; PEP, phosphoenolpyruvate; X-5-P, xylulose-5-phosphate; E-4-P, erythrose-4-phosphate; S-7-P, sedoheptulose-7-phosphate; S-1,7-P, sedoheptulose-1,7-phosphate; R-5-P, ribose-5-phosphate; Ru-5-P, ribulose-5-phosphate.