Phylogenetic tree of Helicobacter pylori housekeeping sequences. The seven concatenated HK genes were biogeographically classified: blue represents European strains (hpEurope), orange indicates the East Asian (hpEastAsia which includes the subpopulations hspAmerindian, hspEastAsian and hspMaorian) isolates, and green denotes African (hpAfrica) strains. The outliers are identified by black arrows (see Discussion for more information).Additional file 3: Table S1 contain label with corresponding MLST/GenBank ID. SeeAdditional file 7: Figure S1 for complete labeling. This radial tree of 393 sequences is the majority rule consensus of 1000 maximum likelihood bootstrap replicates analyzed in PhyML with the GTR + I + G model and visualized in FigTree (see Methods for more details).