HOMIM-based analysis of bacterial growth in the lingual microbiome. (A) Comparison of the number of bacterial species (Species Score) detected by HOMIM assay on the tongue epithelium of healthy HIV- controls, ART naive chronically HIV infected patients, and HIV infected patients on ART. Median values are shown in horizontal bars. (B). HOMIM-based comparison of total bacterial populations (Bacterial Load) on the tongue epithelium of HIV- controls and HIV + patient groups. (C) Correlation between Species Score and Bacterial Load data as determined by Spearman rank correlation coefficient analysis.