Figure 3
E. faecium core and pan genomes. A. E. faecium core genes. The number of shared genes is plotted as the function of number of strains (n) added sequentially. An open circle represents the number of shared genes for each permutation at a give number of strains (n). 1,608 single copy genes are shared by all 22 genomes. The red line represents the least-squares fit to the exponential decay function F c  = κc exp[−n/τ c ] + Ω (κc = 1871 ± 25, τ c  = 1.751 ± 0.027, Ω = 1726 ± 2). B. E. faecium pan-genes. The number of total genes is plotted as the function of strains (n). The open circle represents the number of total genes for each permutation at a give number of strains (n). The red line represents the least-squares fit to the power law function n = κ Nγ (κ = 2876 ± 7, γ = 0.2517 ± 0.009).