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Table 3 Mobile genetic elements carrying erm(B) and mef(E) genes and associated genotypic and phenotypic profiles

From: Dominance of multidrug resistant CC271 clones in macrolide-resistant Streptococcus pneumoniae in Arizona

Population Dual mef(E)/erm(B)- Sequence type 320 Antibiotic susceptiblity profilea PennsEryrClirTetr/u+Sxtr Presumed transposon (no. isolates with same profile tested) Tn2010(12) Total no. isolates of same profile 43
  320 PennsEryrClisTetr/u+Sxtr Tn2010 (1) 2
  320 PennsEryrClirTetu-Sxtr Tn2010 (1) 2
  271 PennsEryrClirTetr/u+Sxtr Tn2010 (5) 7
  1396 PenrEryrClirTetns/u+Sxtr Tn2010 (2) 2
  1396 PenrEryrClisTetns/u+Sxtr Tn2010 (1) 1
  1459 Pen Ery Cli Tet Sxt Tn2010 (3) 3
  3039 Penr/uEryrClirTetr/u+Sxtr Tn2010 (2) 2
  1412 PenrEryrClisTetrSxtr Tn2010 (1) 1
  NF PennsEryrClirTetr/u+Sxtr Tn2010 (5) 6
  NT PennsEryrClirTetr/u+Sxtr NT 3
mef(E)-positive NT PennsEryrClisTetrSxtr NT 1
  236 PennsEryrClisTetr/u+Sxtr Tn2009 (4) 4
  1186 PensErynsClisTets/u-Sxtr mega (4) 4
  1186 PennsEryrClisTetu-Sxtr mega (1) 1
  1379 PennsEryrClisTetsSxtr mega (2) 2
  1379 PensEryrClisTetsSxtr mega (1) 1
  2705 PensEryrClisTets/u-Sxtr mega (3) 3
  3280 PennsEryrClisTetr/u+Sxtr Tn2009 (3) 3
  376 PennsEryrClisTets/u-Sxtr mega (3) 3
  156 PennsEryrClisTets/u-Sxtr mega (2) 2
  199 PensEryrClisTetsSxts mega (1) 1
  199 PennsEryrClisTetu-Sxtr mega (1) 1
  384 PenrEryrClirTets+Sxtr Tn916+mega (1) 1
  384 PenrEryrClisTetrSxts Tn916+mega (1) 1
  13 PenrEryrClisTetsSxtr mega (1) 1
  162 PennsEryrClirTetu-Sxts mega (1) 1
erm(B)-positive 344 PennsEryrClisTetu+Sxtr Tn916+mega (1) 1
  558 PennsEryrClisTetsSxts mega (1) 1
  1518 PennsEryrClisTetsSxtr mega (1) 1
  1556 PenrEryrClisTetu-Sxtr mega (1) 1
  3065 PensEryrClisTetu-Sxtns mega (1) 1
  6422 PenrEryrClisTetrSxtr mega (1) 1
  NF PenrEryrClisTetsSxtns mega (1) 1
  NF PennsEryrClisTetsSxts mega (1) 1
  NF PennsEryrClinsTetu+Sxtr Tn2009 (1) 1
  NT PennsEryrClirTetu+Sxts Tn916+mega (1) 1
  NT PensEryrClisTetsSxtr mega (1) 1
  NT PensEryrClisTetsSxts mega (2) 2
  NT PenrEryrClirTetrSxtr Tn916+mega (1) 1
  NT PenrEryrClirTetu-Sxtr mega (1) 1
  63 Penns/uEryrClirTetr/u+Sxts/u erm(B) element (8) 8
  315 PeniEryrClirTetrSxti Tn916 family (2) 2
  3066 PensEryrClirTetrSxts Tn3872 (1) 1
  180 PensEryrClirTetrSxts Tn916 family (1) 1
  NT PensEryrClirTetrSxts Tn3872 (1) 1
  1. a Pen, penicillin; Ery, erythromycin; Cli, clindamycin; Tet, tetracycline; Sxt, trimethoprim-sulfamethoxazole; r, resistant; ns, nonsusceptible; s, susceptible; u, unknown phenotype; +, positive for tet(M) by PCR; -, negative for tet(M) by PCR; NF, not found; NT, not typed