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Table 1 Characteristics and mechanisms of the 34 fusidic acid-resistant MRSA clinical isolates

From: Fusidic acid resistance among clinical isolates of methicillin-resistant Staphylococcus aureus in a Taiwanese hospital

Isolate Specimen FA
MIC
(μg/ml)
VAN
MIC
(μg/ml)
LZD
MIC
(μg/ml)
OXA
MIC
(μg/ml)
RIF
MIC
(μg/ml)
fusC Polymorphism(s)
inEF-G
PFGE
patterns
1 Pus 8 1 1 >2 < = 0.5 - H457Y A1
2 Pus 32 1 2 >2 < = 0.5 + - A1
3 Pus 8 1 1 >2 < = 0.5 + - A1
4 Sputum 16 1 2 >2 < = 0.5 + H457Y A1
5 Sputum 32 2 2 >2 >2 + - A1
6 Pus 16 1 1 >2 >2 + - A2
7 Pus 8 1 1 >2 < = 0.5 + - A3
8 Sputum 16 1 1 >2 < = 0.5 + - A3
9 Pus 16 1 1 >2 < = 0.5 - G556S A3
10 Sputum 16 1 1 >2 < = 0.5 - H457Y, G556S A3
11 Ascites 8 1 1 >2 < = 0.5 - H457Y A3
12 Pus 64 2 2 >2 < = 0.5 + - A3
13 Sputum 64 2 2 >2 < = 0.5 - H457Y A3
14 Pus 16 1 1 >2 < = 0.5 + - A3
15 Blood 4 1 1 >2 < = 0.5 + - A3
16 Pus 8 1 1 >2 < = 0.5 + - A3
17 Blood 8 1 1 >2 < = 0.5 + - A3
18 Blood 16 1 1 >2 < = 0.5 + - A3
19 Blood 16 1 1 >2 < = 0.5 + - A3
20 Pus 2 2 1 >2 < = 0.5 + - A3
21 Urine 2 2 2 >2 < = 0.5 - H457Y, G556S A3
22 Sputum 2 2 2 >2 < = 0.5 + - A3
23 Pus 16 2 1 >2 >2 - H457Y A4
24 Pus 2 1 1 >2 < = 0.5 + - A5
25 Urine 16 1 1 >2 < = 0.5 + - A6
26 CVP tip 8 1 2 >2 < = 0.5 + - A6
27 Pus 2 2 2 >2 < = 0.5 + - A6
28 Sputum 16 1 2 >2 < = 0.5 + - A7
29a Pus 8 1 2 >2 < = 0.5 + - A8
30 Sputum 16 1 2 >2 < = 0.5 + - A9
31 Pus 16 1 2 >2 < = 0.5 - H457Y, R659L A9
32 Sputum 8 1 2 >2 < = 0.5 + - A9
33 Blood 16 1 1 >2 < = 0.5 - G556S A9
34 Pus 2 2 2 >2 < = 0.5 + - A9
  1. FA, fusidic acid; VAN, vancomycin; LZD, linezolid; OXA, oxacillin; RIF, rifampin
  2. a nonsense mutation in fusC (S175 was encoded by TAA rather than TCA)