Table 4 Comparative analysis of the allelic variation in bla locus for MRSA and MSSA strains
No. isolates | No. alleles | Simpson's | Unique SNP | SNP/allele (average) | Mutations per allele (average) | dN/dS | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | CI (95%) | Silent | Conserv. | Missense | Nonsense | Average | St. dev. | ||||||
blaZ | 54 | 11 | 79.2 | 69.6-88.8 | 41 | 11.4 | 5.3 | 1.7 | 3.7 | 0.1 | 0.21 | 0.11 | |
MRSA | blaI | 27 | 7 | 82.1 | 74.6-89.5 | 10 | 3.9 | 2.9 | 0 | 1.0 | 0 | 0.11 | 0.05 |
blaR1 | 31 | 10 | 88.8 | 83.2-94.4 | 60 | 24.4 | 9.7 | 5.3 | 8.0 | 0 | 0.24 | 0.11 | |
blaZ | 24 | 9 | 76.1 | 61.3-90.9 | 35 | 14.7 | 7.1 | 1.9 | 4.6 | 0 | 0.17 | 0.04 | |
MSSA | blaI | 20 | 6 | 74.2 | 60.5-87.9 | 9 | 2.5 | 1.5 | 0.2 | 0.8 | 0 | 0.08 | 0.03 |
blaR1 | 17 | 8 | 88.2 | 81.2-95.3 | 61 | 24.6 | 10.4 | 5.5 | 7.8 | 0 | 0.24 | 0.10 | |
blaZ | 78 | 13 | 81.1 | 75.0-87.3 | 43 | 12.4 | 5.8 | 1.8 | 4.0 | 0.1 | 0.20 | 0.10 | |
All | blaI | 47 | 9 | 78.4 | 71.0-85.9 | 13 | 3.4 | 2.3 | 0.1 | 1.0 | 0 | 0.10 | 0.04 |
blaR1 | 48 | 12 | 88.5 | 84.0-93.0 | 65 | 24.8 | 10.2 | 5.3 | 8.1 | 0 | 0.25 | 0.10 | |