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Table 3 Hemolysis, DNA fragmentation, cytotoxicity, and metabolic activity of Campylobacter concisus isolatesa.

From: Comparative genotypic and pathogenic examination of Campylobacter concisusisolates from diarrheic and non-diarrheic humans

Isolate AFLP
Cluster
Hemolysisb
(%)
DNA fragmentationc
(A370 nm)
Cytotoxicityc
(%)
Metabolic activity c
(% control)
CHRB2004 1 60.2 ± 14.4 1.84 ± 0.17d 1.23 ± 0.21 139.4 ± 7.4
CHRB3287 1 45.6 ± 16.9 1.83 ± 0.13d 1.48 ± 0.16 146.8 ± 9.2
CHRB2011 1 60.5 ± 9.8 1.63 ±.0.05d 0.88 ± 0.22 151.9 ± 7.5
CHRB3290 1 81.1 ± 4.5 1.91 ± 0.14d 0.94 ± 0.19 155.7 ± 2.3
CHRB1609 1 72.3 ± 9.4 1.37 ± 0.18 1.11 ± 0.34 144.5 ± 4.4
CHRB1794 2 70.9 ± 10.1 1.32 ± 0.19 1.42 ± 0.15 137.9 ± 2.9
CHRB6 2 41.2 ± 11.6 1.12 ± 0.26 1.43 ± 0.18 105.1 ± 26.2e
CHRB1569 2 47.0 ± 12.0 1.38 ± 0.17 1.29 ± 0.26 139.2 ± 7.0
CHRB2691 2 62.1 ± 14.3 1.62 ± 0.07d 1.89 ± 0.15 133.5 ± 10.3
CHRB2370 2 44.9 ± 12.0 1.69 ± 0.14d 1.46 ± 0.08 142.8 ± 6.5
CHRB2050 2 64.3 ± 15.4 1.41 ± 0.07 0.97 ± 0.15 131.0 ± 7.1
CHRB563 2 34.6 ± 13.9 1.55 ± 0.23d 1.25 ± 0.20 138.0 ± 10.2
CHRB3152 2 30.7 ± 15.4 1.89 ± 0.16d 1.28 ± 0.15 141.0 ± 6.0
CHRB3235 2 32.1 ± 18.6 1.69 ± 0.12d 1.14 ± 0.16 143.2 ± 6.3
LMG7788 1 61.5 ± 10.8 1.54 ± 0.08d 0.71 ± 0.10 140.8 ± 5.2
C. jejuni 81-176 -- 75.6 ± 3.7 1.68 ± 0.25d 4.53 ± 0.31d 143.7 ± 5.7
Broth control -- 0.44 ± 0.14 0.69 ± 0.12 0.96 ± 0.34 100
H2O2 -- -- 1.38 ± 0.22 6.15 ± 1.66d 259.5 ± 13.5
Camptothecin -- -- 2.23 ± 0.40d 1.39 ± 0.28 177.5 ± 9.2
  1. a Data are means ± SEM, n = 3.
  2. b Percent total hemolysis of sheep erythrocytes for 1/8 dilution of Campylobacter inoculum.
  3. c Assays conducted using T84 monolayers
  4. d P < 0.05 relative to the broth control treatment.
  5. e Sloughing of epithelial cells noted in two of three repetitions.