Table 1 Polymorphisms in the genes of mce1 operon.
mce1operon | ||||||||
|---|---|---|---|---|---|---|---|---|
Gene Name (Accession Number) | Nucleotide Change [GenBank Accession Number] | Amino Acid Change | Frequency Distribution of polymorphism (%) | |||||
| Â | Â | Non Synonymous | Synonymous | All isolates n = 112 | DS n = 22 | DR n = 59 | SDR n = 15 | MDR TB n = 19 |
yrbE1A [Rv0167] | C14T [GenBank:HQ901088] | Thr5Ile | NONE | (25.96) | (29.16) | (29.09) | (41.76) | (15.78) |
yrbE1B [Rv0168] | T154G [GenBank:HQ901089] | Tyr52Asp | NONE | (0.9) | NONE | (1.72) | NONE | (5.26) |
mce1A [Rv0169] | C1075T C1323T [GenBank:HQ901082] | Pr0359Ser | Tyr441Tyr | (1.87) | (4) | NONE | NONE | NONE |
mce1B [Rv0170] | T536C [GenBank:HQ901085] | Ile179Thr | NONE | (0.9) | (3.8) | NONE | NONE | NONE |
mce1C [Rv0171] | G636C [GenBank: HQ901086] | Glu212Asp | NONE | (0.9) | (3.8) | NONE | NONE | NONE |
mce1D [Rv0172] | NONE | NONE | NONE | NONE | NONE | NONE | NONE | NONE |
lprK [Rv0173] | NONE | NONE | NONE | NONE | NONE | NONE | NONE | NONE |
mce1F [Rv0174] | G129T [GenBank: HQ901083] | Lys43Asn | NONE | (0.9) | (4) | NONE | NONE | NONE |