Figure 3
From: Arcanolysin is a cholesterol-dependent cytolysin of the human pathogen Arcanobacterium haemolyticum
Salient features of the ALN predicted amino acid sequence. (a) ALN sequence with predicted signal sequence (underlined), putative PEST motif (inverse), undecapeptide (bold), and cholesterol-interacting TL motif (double underlined). (b) Undecapeptide sequences of ALN, other CDC undecapeptides known to differ from consensus, and the consensus CDC undecapeptide. The cysteine conserved in thiol-activated CDCs (but absent from ALN) is underlined in the consensus sequence. Differences from consensus depicted as inverse letters. Abbreviations as in Figure 2.