Skip to main content


Figure 2 | BMC Microbiology

Figure 2

From: Specific antibody-receptor interactions trigger InlAB-independent uptake of listeria monocytogenes into tumor cell lines

Figure 2

Internalization of Cetuximab- or Trastuzumab- coated Lm-spa+ relative to uncoated Lm-spa+ (-mAb) into different cell lines. (a) Mouse mammary cancer cell line 4T1, the HER2 transduced isogenic 4T1-HER2 and (b) the human mammary/ovary cancer cell lines SK-BR-3 and SK-OV-3, respectively, were infected with Lm-spa+ after coating with different antibodies. Intracellular colony forming units (CFU) were determined after gentamicin treatment by serial plating and the internalization rate of the antibody-coated relative to the uncoated bacteria was calculated.

Back to article page