Table 1 The profile of proinflammatory cytokine and chemokine secretion of iDCs in response to C. parapsilosis
iDC (24 h) | |||
|---|---|---|---|
(pg/ml) | unstimulated | Cpwt | Cplip-/- |
IL-1 α | 9.38† (8.20-11.19) | 10.01 (8.34-11.17) | 23.60# (19.88-26.74) |
IL-6 | 175.77 (48.34-252.62) | 3059.61 (1689.8-5880.12) | 5636.54# (2792.25-7915.07) |
TNF α | 74.36 (55.71-115.78) | 624.47 (522.57-736.08) | 2836.59# (2822.29-3147.02) |
CXCL8 | 794.23 (162.80-1226.77) | 3622.8 (2047-5297.31) | 3023.9 (1226.41-5297.31) |
iDC (48 h) | |||
(pg/ml) | unstimulated | Cp wt | Cp lip-/- |
IL-1 α | 7.85 (5.05-12.31) | 15.45 (8.34-21.56) | 22.14 (19.88-26.74) |
IL-6 | 3573.23 (3201.12-4752.01) | 5238.9 (3767.13-6082.85) | 6968.16# (5398-8938.58) |
TNF α | 154.92 (115.71-194.82) | 2342.12 (649.76-4333.62) | 3947.27# (2433.01-5393.78) |
CXCL8 | 1103.05 (656.02-1473.77) | 1615.33 (942.11-1756.85) | 1824.31 (1226.41-2491.06) |