Figure 9

Genes with positively selected amino acid changes between East Asian and non-East Asian strains. (A) Position of the positively selected amino-acid residues in ORF (triangles). In (i), EPIYA segments and CM sequences [138] are marked. (B) Position of positively selected amino acids in the three-dimensional structure. (i) HpaA-2 [PDB:2I9I]. (ii) E. coli MiaA [PDB:3FOZ] [61] with the residue corresponding to H174 of H. pylori MiaA. (iii) p55 fragment of VacA [PDB:2QV3] [61] (Table 7).