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Figure 3 | BMC Microbiology

Figure 3

From: Serotype- and strain- dependent contribution of the sensor kinase CovS of the CovRS two-component system to Streptococcus pyogenes pathogenesis

Figure 3

Biofilm formation abilities of CovS mutant strains and corresponding parental strains in different GAS serotypes. A. M49::covS, M49_581::covS and M49_634::covS mutants, and the correspondent wild type M49 GAS strains. B. M2::covS and M2_583::covS mutants and the correspondent wild type M2 GAS strains. C. M18_588::covS mutant and wild type M18_588 GAS strain. D. M6_586::covS, M6::covS, M6_796::covS and M6_576::covS mutants and the correspondent wild type M6 GAS strains. The biofilm production under static conditions in BHI media supplemented with 0.5% (w/v) glucose was quantified by safranin assay. The incubation time is presented in hours (h). The surfaces for biofilm formation were either non-coated (Ncp, no coating protein) or coated with fibronectin (Fn). Data reported represent the mean and standard error of the mean derived from three independent experiments. The significance level as determined by two-tailed paired Student's t test is indicated (*).

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