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Figure 1 | BMC Microbiology

Figure 1

From: Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2-heptylquinoline-N- oxide

Figure 1

HQNO inhibits the growth of normal S. aureus strains and provokes the emergence of SCVs. (A) Growth curves of the normal strain CF1A-L (□) and the SCV CF1D-S (●) exposed (dotted lines) or not (solid lines) to 10 μg/ml of HQNO. (B) Pictures show SCV colonies grown on agar containing a selective concentration of gentamicin following or not an overnight treatment of strain CF1A-L with 10 μg/ml of HQNO. (C) Relative number of SCV CFUs recovered after 18 h of growth from strains ATCC 29213, Newman, Newbould, CF03-L, CF07-L and CF1A-L following (black bars) or not (open bars) treatments with 10 μg/ml of HQNO. Data are presented as means with standard deviations from at least three independent experiments. Results are normalized to the non exposed condition for each strain (dotted line). Significant differences between untreated and HQNO-treated conditions are shown (*, P < 0.05; **, P < 0.01; ***, P < 0.001; unpaired t- test).

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BMC Microbiology

ISSN: 1471-2180

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