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Table 7 Summary of publications regarding the role for Salmonella AvrA in monolayers, drosophila, and mouse models.

From: Eukaryotic signaling pathways targeted by Salmonella effector protein AvrA in intestinal infection in vivo

Models

Pathways

References

Monolayers

Tight-junction pathway

Liao et al., PLoS One. 2008 3(6):e236

 

Activated β-catenin pathway

Sun et al., Am J Physiol Gastrointest Liver Physiol. 2004 287(1):G220-7

 

Inhibited NF-κB pathway

Ye et al., Am J Pathol. 2007 171(3):882-92

 

Inhibited NF-κB pathway

Collier-Hyams et al., J Immunol. 2002 169(6):2846-50

 

Inhibited JNK pathway

Du and Galan, PLoS Pathog. 20095(9): e1000595

 

Inhibited JNK pathway

Jones et al, Cell Host Microbe. 2008 3(4):233-44

Drosophila

Inhibited JNK, NF-κB pathway

Jones et al, Cell Host Microbe. 2008 3(4):233-44

Mouse

Inhibited JNK, NF-κB pathway

Jones et al, Cell Host Microbe. 2008 3(4):233-44

 

Inhibited NF-κB pathway

Ye et al., Am J Pathol. 2007 171(3):882-92

 

Activated P53 pathway

Wu et al., Am J Physiol Gastrointest Liver Physiol. 2010 298(5):G784-94.

 

Tight-junction pathway

Liao et al., PLoS One. 2008 Jun 4;3(6):e236

 

Activated β-catenin pathway β

Ye et al., Am J Pathol. 2007 Sep;171(3):882-92

 

Activated Wnt/β-catenin Pathway

Liu et al., FEBS Letter, 2010 584(5):911-916