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Figure 2 | BMC Microbiology

Figure 2

From: Superoxide dismutase is upregulated in Staphylococcus aureus following protoporphyrin-mediated photodynamic inactivation and does not directly influence the response to photodynamic treatment

Figure 2

Mn ions influence on protoporphyrin IX-mediated PDI against reference strains. The bacterial suspensions were illuminated after dark incubation for 30 min. at 37°C with different concentrations of PpIX (up to 50 μM). PDI was tested against reference strains of S. aureus: RN6390, RN6390sodA, RN6390sodM, RN6390sodAM in Mn-supplemented medium (A) and Mn-depleted medium (B). Bacteria were illuminated with 12 J/cm2 624 ± 18 nm light, and survival fractions were determined as described in Methods. Values are means of three separate experiments, and bars are SD. * indicates statistically significant difference in survival drop between RN6390sodAM and each of the following strains RN6390, RN6390sodA, RN6390sodM at each tested concentration (p < 0.05).

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BMC Microbiology

ISSN: 1471-2180

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