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Table 1 MIC values of host defence peptides against S. aureus and L. monocytogenes wild types and two-component system mutants.

From: The heme sensing response regulator HssR in Staphylococcus aureus but not the homologous RR23 in Listeria monocytogenes modulates susceptibility to the antimicrobial peptide plectasin

  

MIC (μg/ml)

Strain

Description

Plec

Euro

Prot

NovC

NovS

8325-4

S. aureus wild type

16

32

16

1

128

8325-4 hssR::bursa

Transposon mutant

32

64

16

1

128

8325-4 hssR::bursa/pRMC2-hssRS

Complementation of hssR transposon mutant

16

32

nd

nd

nd

8325-4 hssR

Transduced 8325-4 hssR mutant

32

64

16

1

128

15981

S. aureus wild type

8

8

16

1

>128

15981 ΔTCS15 (hssRS)

hssRS deletion mutant

32

32

16

1

>128

LO28

L. monocytogenes wild type

64

128

16

1

16

LO28 RR23

rr23 insertion mutant

64

128

16

1

16

  1. Plec: plectasin, Euro: eurocin, Prot: protamine, NovC: novicidin, NovS: novispirin. nd: not determined.