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Table 1 Results of pncA gene sequencing of 150 M. tuberculosis clinical isolates.

From: Erratum to: Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand

    pncA mutation
M. tuberculosis strains (no. of isolates) MGIT 960 PZase assay Nucleotide change Amino acid change
Susceptible (46) S + wild-type no
Susceptible (1) S + T92G Ile31Ser
Susceptible (2) R + wild-type wild-type
Susceptible (1) R + T92C Ile31Thr
MDR-TB (42) S + wild-type wild-type
MDR-TB (9) S + T92C Ile31Thr
MDR-TB (34) R - A(-11)G (1) no
    A(-11)C (1) no
    T56G (1) Leu19Arg
    T80C (1) Leu27Pro
    T92G (2) Ile31Ser
    T104C (1) Leu35Pro
    T134C (1) Val45Ala
    G136T (1) Ala46Ser
    T199C (1) Ser67Pro
    C211G (8) His71Asp
    G215A (1) Cys72Tyr
    G289A (3) Gly97Ser
    C312G (2) Ser104Arg
    G322C (1) Gly108Arg
    G373T (1) Val125Phe
    G379T (1) Glu 127 Stop
    G394A (1) Gly132Ser
    G insertion b/w 411-412 (1)  
    T416G (1) Val 139 Gly
    C425T (1) Thr 142 Met
    G436A (1) Ala 146 Thr
    GG insertion b/w 520-521 (1)  
    C530T (1) Thr 177 Ile
MDR-TB (11) R + wild-type no
MDR-TB (4) R + T92C (3) Ile31Thr
    T92G (1) Ile31Ser