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Table 1 List of commonly upregulated genes for all pathogens.

From: Gram-positive pathogenic bacteria induce a common early response in human monocytes

     Fold Change
No. Gene IDs Gene Symbol Gene name LM SA SP
1 51561 IL23A Interleukin 23, alpha subunit p19"" 48,15 30,02 6,70
2 57124 CD164L1 CD248 antigen, endosialin"" 20,36 22,03 8,23
3 3426 IF I factor (complement) 17,07 13,08 6,88
4 10411 RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 13,85 11,81 5,60
5 1960 EGR3 Early growth response 3 12,16 8,98 2,65
6 3725 JUN V-jun sarcoma virus 17 oncogene homolog (avian) 10,80 12,09 6,35
7 9389 SLC22A14 Solute carrier family 22 (organic cation transporter), member 14"" 10,41 9,29 5,40
8 6648 SOD2 Superoxide dismutase 2, mitochondrial"" 10,24 8,61 4,23
9 3290 HSD11B1 Hydroxysteroid (11-beta) dehydrogenase 1 10,04 20,04 5,73
10 122616 C14orf79 Chromosome 14 open reading frame 79 9,27 8,15 4,45
11 4790 NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) 8,03 8,17 3,06
12 131566 DCBLD2 Discoidin, CUB and LCCL domain containing 2"" 7,94 5,46 4,59
13 1906 EDN1 Endothelin 1 7,76 10,71 3,40
14 9025 RNF8 Ring finger protein 8 7,38 6,01 2,98
15 51458 RHCG Rhesus blood group, C glycoprotein"" 6,90 8,94 2,55
16 1735 DIO3 Deiodinase, iodothyronine, type III"" 6,83 6,20 3,70
17 9021 SOCS3 Suppressor of cytokine signaling 3 6,82 9,90 3,10
18 83740 H2AFB3 H2A histone family, member B3"" 6,69 8,58 3,55
19 9028 RHBDL1 Rhomboid, veinlet-like 1 (Drosophila)"" 6,18 5,07 2,28
20 8659 ALDH4A1 Aldehyde dehydrogenase 4 family, member A1"" 6,13 3,74 3,02
21 8740 TNFSF14 Tumor necrosis factor (ligand) superfamily, member 14"" 5,74 3,83 1,60
22 51025 Magmas Mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction 5,52 5,54 3,11
23 10120 ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)"" 5,17 4,63 2,70
24 2615 GARP Leucine rich repeat containing 32 4,96 3,18 3,03
25 55655 NALP2 NACHT, leucine rich repeat and PYD containing 2"" 4,72 4,59 2,83
26 6004 RGS16 Regulator of G-protein signalling 16 4,66 2,42 2,22
27 6935 TCF8 Transcription factor 8 (represses interleukin 2 expression) 4,66 2,81 7,11
28 3280 HES1 Hairy and enhancer of split 1, (Drosophila)"" 4,65 4,37 2,02
29 983 CDC2 Cell division cycle 2, G1 to S and G2 to M"" 4,64 4,21 2,31
30 9076 CLDN1 Claudin 1 4,60 4,85 2,59
31 10307 APBB3 Amyloid beta (A4) precursor protein-binding, family B, member 3"" 4,53 3,47 2,90
32 283131 TncRNA Trophoblast-derived noncoding RNA 4,29 5,03 2,53
33 114112 TXNRD3 Thioredoxin reductase 3 4,15 3,55 2,01
34 6355 CCL8 Chemokine (C-C motif) ligand 8 4,06 3,54 2,54
35 1164 CKS2 CDC28 protein kinase regulatory subunit 2 3,95 3,12 2,11
36 5142 PDE4B Phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)"" 3,93 3,93 2,35
37 6358 CCL14 Chemokine (C-C motif) ligand 14 3,80 4,33 3,76
38 788 SLC25A20 Solute carrier family 25 (carnitine/acylcarnitine translocase), member 20"" 3,72 3,69 2,55
39 3697 ITIH1 Inter-alpha (globulin) inhibitor H1 3,71 3,12 2,05
40 2322 FLT3 Fms-related tyrosine kinase 3 3,66 4,59 2,20
41 6489 SIAT8A ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1"" 3,47 3,23 2,67
42 23529 CLC Cardiotrophin-like cytokine factor 1 3,33 7,64 2,12
43 55647 RAB20 RAB20, member RAS oncogene family"" 3,31 3,86 3,95
44 54847 SIDT1 SID1 transmembrane family, member 1"" 3,15 4,43 2,78
45 10514 MYBBP1A MYB binding protein (P160) 1a 3,09 5,53 2,35
46 64108 IFRG28 28 kD interferon responsive protein 3,08 2,48 2,22
47 9590 AKAP12 A kinase (PRKA) anchor protein (gravin) 12 2,99 2,72 2,09
48 5894 RAF1 V-raf-1 murine leukemia viral oncogene homolog 1 2,97 2,75 2,19
49 51365 PLA1A Phospholipase A1 member A 2,95 4,52 2,45
50 6696 SPP1 Secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)"" 2,93 5,05 1,70
51 1939 LGTN Ligatin 2,80 3,90 2,15
52 57801 HES4 Hairy and enhancer of split 4 (Drosophila) 2,78 2,72 2,13
53 3202 HOXA5 Homeo box A5 2,76 2,07 2,37
54 4216 MAP3K4 Mitogen-activated protein kinase kinase kinase 4 2,68 3,54 2,05
55 481 ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide"" 2,65 2,04 2,27
56 1466 CSRP2 Cysteine and glycine-rich protein 2 2,64 8,75 3,66
57 11182 SLC2A6 Solute carrier family 2 (facilitated glucose transporter), member 6"" 2,48 2,46 2,00
58 83660 TLN2 Talin 2 2,41 2,26 2,21
59 7003 TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 2,40 1,92 2,11
60 85378 TUBGCP6 Tubulin, gamma complex associated protein 6"" 2,40 2,72 2,46
61 1846 DUSP4 Dual specificity phosphatase 4 2,38 2,92 2,60
62 7422 VEGF Vascular endothelial growth factor 2,30 2,27 2,10
63 10560 SLC19A2 Solute carrier family 19 (thiamine transporter), member 2"" 2,10 2,45 2,90
64 6617 SNAPC1 Small nuclear RNA activating complex, polypeptide 1, 43 kDa"" 2,05 2,65 2,38
65 6515 SLC2A3 Solute carrier family 2 (facilitated glucose transporter), member 3"" 2,04 2,57 2,36
66 136 ADORA2B Adenosine A2b receptor 1,90 1,79 1,72
  1. FDR 10. LM: L. monocytogene s EGDe, SA: S. aureu s, SP: S. pneumoniae.