Table 2 List of the 23 differentially expressed proteins found in rifampicin resistant Neisseria meningitidis strains
From: Neisseria meningitidis rifampicin resistant strains: analysis of protein differentially expressed
Spot n | Protein name (gene) a | Protein accession number | Ordered Locus Nameb | Sequence coverage % | Mowse Score | MWt/pIt | Expression level c | UniProtKB Functional classification d |
|---|---|---|---|---|---|---|---|---|
1 | Aconitate hydratase (acn B) | A1KUZ6 | NMC1492 | 51 | 403 | 93412/5.38 | up | Carbohydrate metabolism: TCA cycle |
2 | Piruvate dehydrogenase subunit E1 (ace E) | A1KUG5 | NMC1278 | 53 | 426 | 99915/5.60 | up | Carbohydrate metabolism: pyruvate metabolism |
3 | Putative phosphoenolpyruvate synthase (pps A) | A1KSM6 | NMC0561 | 26 | 165 | 87128/6.01 | up | Carbohydrate metabolism: pyruvate metabolism |
4 | Elongation factor G (fus A) | A1KRH0 | NMC0127 | 30 | 245 | 77338/5.08 | up | Genetic Information Processing: protein synthesis |
5 | Isocitrate dehydrogenase (icd) | A1KTJ0 | NMC0897 | 27 | 229 | 80313/5.53 | up* | Carbohydrate metabolism: TCA cycle |
6 | 60 kDa chaperonin (gro L) | A1KW52 | NMC1948 | 41 | 206 | 57535/4.90 | down | Genetic Information Processing: protein folding |
7 | ATP synthase subunit α (atp A) | A1KW13 | NMC1908 | 62 | 281 | 55481/5.50 | down | Energy metabolism: oxidative phosphorilation |
8 | N utilisation substance protein A (nus A) | A1KV50 | NMC1556 | 71 | 426 | 55745/4.54 | up | Genetic Information Processing: protein synthesis |
9 | Putative phosphate acyltransferase (NMC0575) | A1KSN9 | NMC0575 | 47 | 263 | 57551/5.47 | up* | Carbohydrate metabolism: propanoate metabolism |
10 | Probable malate:quinone oxidoreductase (mqo) | A1KWH2 | NMC2076 | 36 | 178 | 54091/5.58 | down | Carbohydrate metabolism: TCA cycle |
11 | Trigger factor (tig) | A1KUE0 | NMC1250 | 51 | 209 | 48279/4.76 | down | Genetic Information Processing: protein folding |
12 | Enolase (eno) | A1KUB6 | NMC1220 | 25 | 129 | 46319/4.78 | down | Carbohydrate metabolism: glycolysis |
13 | Cell division protein (fts A) | A1KVK9 | NMC1738 | 40 | 132 | 44348/5.33 | down | Genetic Information Processing: cell division |
14 | Glutamate dehydrogenase (gdh A) | A1KVB4 | NMC1625 | 54 | 221 | 48731/5.80 | up | Energy metabolism: amino acid metabolism |
15 | Putative zinc-binding alcohol dehydrogenase (NMC0547) | A1KSL2 | NMC0547 | 38 | 235 | 38283/5.32 | down* | Carbohydrate metabolism: butanoate metabolism |
16 | Succinyl-CoA ligase [ADP-forming] subunit beta (suc C) | A1KTM6 | NMC0935 | 26 | 125 | 41567/5.01 | up | Carbohydrate metabolism: TCA cycle |
17 | DNA-directed RNA polymerase subunit α (rpo A) | A1KRJ9 | NMC0158 | 41 | 184 | 36168/4.94 | up | Genetic Information Processing: transcription |
18 | Carboxyphosphonoenol pyruvate phosphonomutase (prp B) | A1KVK6 | NMC1733 | 73 | 234 | 31876/5.22 | down | Carbohydrate metabolism: propanoate metabolism |
19 | Putative malonyl Co-A acyl carrier protein transacylase (fab D) | A1KRY7 | NMC0305 | 57 | 158 | 31958/5.44 | down | Lipid metabolism: fatty acid biosynthesis |
20 | Septum site-determining protein (min D) | A1KRK2 | NMC0161 | 29 | 143 | 29768/5.70 | down | Genetic Information Processing: cell division |
21 | Putative two-component system regulator (NMC0537) | A1KSK4 | NMC0537 | 74 | 181 | 24821/5.44 | down | Environmental Information Processing: signal transduction |
22 | Peptidyl-prolyl cis-trans isomerase (ppi B) | A1KT50 | NMC0744 | 84 | 260 | 18840/5.04 | down | Genetic Information Processing: protein folding |
23 | Putative oxidoreductase (NMC0426) | A1KSA1 | NMC0426 | 52 | 129 | 20759/5.74 | down* | - |