Table 3 Performance of the rAtpD, rP1-C ELISAs and the Ani Labsystems kit in adults
Ig class | Type of test | No. of positive sera in | Sensitivity (95% CI) | Specificity (95% CI) | AUC | |
|---|---|---|---|---|---|---|
Patientsa (49) | Controlsb (86) | |||||
M | rAtpD | 33 | 8 | 67% (54%-80%) | 91% (85%-97%) | 0.877 |
M | rP1-C | 22 | 9 | 45% (31%-59%) | 90% (83%-96%) | 0.708 |
M | rAtpD-rP1-C | 39 | 7 | 80% (68%-91%) | 92% (86%-98%) | 0.891 |
M | Ani Labsystems | 24 | 7 | 49% (35%-61%) | 92% (81%-97%) | 0.685 |
A | rAtpD | 32 | 5 | 65% (52%-78%) | 94% (89%-99%) | 0.894 |
A | rP1-C | 27 | 9 | 55% (41%-69%) | 90% (83%-96%) | 0.779 |
A | rAtpD-rP1-C | 36 | 9 | 73% (61%-86%) | 90% (83%-96%) | 0.841 |
A | Ani Labsystems | 48 | 38 | 98% (94%-100%) | 56% (45%-66%) | 0.803 |
G | rAtpD | 30 | 3 | 61% (48%-75%) | 97% (93%-100%) | 0.877 |
G | rP1-C | 22 | 9 | 45% (31%-59%) | 90% (83%-96%) | 0.708 |
G | rAtpD-rP1-C | 33 | 1 | 67% (54%-80%) | 99% (97%-100%) | 0.891 |
G | Ani Labsystems | 48 | 61 | 98% (94%-100%) | 29% (19%-39%) | 0.734 |