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Table 2 List of genes that are downregulated upon P. acnes infection.

From: Propionibacterium acnes infection induces upregulation of inflammatory genes and cytokine secretion in prostate epithelial cells

Gene name Description Fold upregulation
FOS V-fos FBJ murine osteosarcoma viral oncogene homolog -3
HMGB1 High-mobility group box 1 -3
TLR4 Toll-like receptor 4 -4
UBE2V1 Ubiquitin-conjugating enzyme E2 variant 1 -3
  1. Semiconfluent RWPE-1 monocell-layers were infected with P. acnes at a MOI of 16:1. After 24 h infection, the cells were harvested, mRNA was collected and cDNA was prepared. The cDNA corresponding to 84 inflammation-associated genes was quantified with qRT-PCR and compared with cDNA prepared from non-infected cells. Inclusion criteria: > 2-fold down-regulation, (p = 0.05).