Table 2 Fluoroquinolone activity on strains grown after single step selection in E. coli and Klebsiella spp. at plasma concentrations
Drug | MIC range (mg/L)/number of strains grown | |||
|---|---|---|---|---|
| Â | E. coli (n = 20) | Klebsiella spp (n = 20) | ||
| Â | Cmax | Cmin* | Cmax | Cmin* |
LVX 500 mg | -/0 | 1/1 | -/0 | 0.5 - 4/16 |
LVX 750 mg | -/0 | 1 - 4/2 | -/0 | 1 - 8/14 |
CIP 500 mg | -/0 | 0.25 - 0.5/4 | -/0 | 0.125 - 4/20 |
PRU 600 mg | 2 - 4/3 | 0.25 - 2/5 | 4 - 8/5 | 0.06 - 1/20 |