Table 1 Comparison of resistance rates of E. coli isolated from urine and blood cultures; and between integron positive and negative isolates from both these sources
Antibiotics | Overall resistance of E. coli from all isolates n = 470 | Resistance rates of E. coli from urine cultures n = 361 (%) | Resistance rates of E. coli from blood cultures n = 109 (%) | p value | Resistance rate of E. coli from urine cultures | Resistance rates of E. coli from blood cultures | ||||
|---|---|---|---|---|---|---|---|---|---|---|
Integron positive n = 66 (%) | Integron negative n = 295 (%) | p value | Integron positive n = 26 (%) | Integron negative n = 83 (%) | p value | |||||
Ampicillin | 210 (77.4)# | 161 (73.9)$ | 49 (92.5)^ | 0.948 | 23 (82.1)° | 138 (72.6)¥ | 0.285 | 12 (92.3)Ω | 37 (92.5)□ | 1 |
Amikacin | 28 (6) | 19 (5.3) | 9 (8.3) | 0.247 | 8 (12.1) | 11 (3.7) | 0.006* | 1 (3.8) | 8 (9.6) | 0.683 |
Amoxicillin clavulanic acid | 211 (44.9) | 159 (44) | 52 (47.7) | 0.501 | 38 (57.6) | 121 (41) | 0.014* | 15 (57.7) | 37 (44.6) | 0.243 |
Cefepime | 182 (38.7) | 123 (34.1) | 59 (54.1) | < 0.001* | 33 (50) | 90 (30.5) | 0.003* | 17 (65.4) | 42 (50.6) | 0.187 |
Cefoperazone sulbactam | 71 (15.1) | 52 (14.4) | 19 (17.4) | 0.439 | 19 (28.8) | 33 (11.2) | < 0.01* | 6 (23.1) | 13 (15.7) | 0.385 |
Ceftriaxone | 324 (68.9) | 236 (65.4) | 88 (80.7) | 0.002* | 47 (71.2) | 189 (64.1) | 0.27 | 21 (80.8) | 67 (80.7) | 1 |
Cefuroxime | 353 (75.1) | 258 (71.5) | 95 (87.2) | 0.001* | 52 (78.8) | 206 (69.8) | 0.175 | 23 (88.5) | 72 (86.7) | 1 |
Ciprofloxacin | 359 (76.4) | 262 (72.6) | 97 (89) | < 0.01* | 61 (92.4) | 201 (68.1) | < 0.01* | 24 (92.3) | 73 (88) | 0.727 |
Ertapenem | 59 (12.6) | 43 (11.9) | 16 (14.7) | 0.445 | 15 (22.7) | 28 (9.5) | 0.003* | 5 (19.2) | 11 (13.3) | 0.452 |
Gentamicin | 128 (27.2) | 98 (27.1) | 30 (27.5) | 0.938 | 21 (31.8) | 77 (26.1) | 0.345 | 6 (23.1) | 24 (28.9) | 0.561 |
Imipenem | 47 (10) | 35 (9.7) | 12 (11) | 0.689 | 13 (19.7) | 22 (7.5) | 0.002* | 3 (11.5) | 9 (10.8) | 1 |
Meropenem | 46 (9.8) | 36 (10) | 10 (9.2) | 0.806 | 13 (19.7) | 23 (7.8) | 0.004* | 2 (7.7) | 8 (9.6) | 1 |
Nalidixic acid | 226 (83.3)# | 178 (81.7)$ | 48 (90.6)^ | < 0.001* | 27 (96.4)° | 151 (79.5)¥ | 0.034* | 12 (92.3) Ω | 36 (90)□ | 1 |
Nitrofurantoin | 29 (10.7)# | 17 (7.8)$ | 12 (22.6)^ | 0.002* | 6 (21.4)° | 11 (5.8)¥ | 0.012* | 5 (38.5) Ω | 7 (17.5)□ | 0.117 |
Piperacillin tazobactam | 105 (22.3) | 77 (21.3) | 28 (25.7) | 0.345 | 26 (39.4) | 51 (17.3) | < 0.01* | 10 (38.5) | 18 (21.7) | 0.088 |
Trimethoprim sulphamethoxazole | 219 (46.6) | 157 (43.5) | 62 (56.9) | 0.014* | 55 (83.3) | 102 (34.6) | < 0.01* | 19 (73.1) | 43 (51.8) | 0.056 |