Table 3 Minimal duration of killing of strains MC4100 and its isogenic rpoS mutant and of natural isolates with different RpoS levels. The MDK99 and MDK99.99 were calculated from time-kill curves depicted in Fig. 3
From: RpoS role in antibiotic resistance, tolerance and persistence in E. coli natural isolates
Strain | RpoS level | MDK | Ampicillin | Ciprofloxacin | Kanamycin |
|---|---|---|---|---|---|
MC4100 | 2.5a | MDK99 | 102.57 | 97.77 | 103.95 |
MDK99.99 | 205.13 | 195.55 | 207.91 | ||
BS1154 | 0 | MDK99 | 93.03 | 82.03 | 107.85 |
MDK99.99 | 186.07 | 164.06 | 215.70 | ||
J24 | 0 | MDK99 | NDb | 82.09 | 39.70 |
MDK99.99 | 164.18 | 79.40 | |||
J13 | 0.24 | MDK99 | 133.48 | 54.89 | 22.36 |
MDK99.99 | 266.97 | 109.78 | 44.71 | ||
G20 | 0.26 | MDK99 | 122.48 | 37.75 | 21.32 |
MDK99.99 | 244.96 | 75.49 | 42.64 | ||
F19 | 0.28 | MDK99 | 95.15 | 36.26 | 12.25 |
MDK99.99 | 190.30 | 72.52 | 24.50 | ||
G03 | 0.29 | MDK99 | 120.55 | 66.74 | 12.86 |
MDK99.99 | 241.11 | 133.48 | 25.73 | ||
A05 | 1.72 | MDK99 | 116.88 | 47.77 | 7.94 |
MDK99.99 | 233.76 | 95.54 | 15.88 | ||
I04 | 1.79 | MDK99 | 104.43 | 18.42 | 26.62 |
MDK99.99 | 208.85 | 36.84 | 53.24 | ||
E11 | 1.99 | MDK99 | 100.33 | 88.56 | 26.62 |
MDK99.99 | 200.66 | 177.12 | 53.24 | ||
I12 | 2.22 | MDK99 | 137.78 | 115.13 | 28.08 |
MDK99.99 | 275.76 | 230.26 | 56.16 | ||
I25 | 2.48 | MDK99 | 109.65 | 65.79 | 20.74 |
MDK99.99 | 219.29 | 131.58 | 41.49 |