Fig. 1

Human-derived bacterial strains effectively alleviated the severity of DSS-induced colitis in vivo. (a) Percentage of body weight changes at day 5 after DSS administration. (b) Colon length of mice at day 5 after DSS administration. (c) Quantification of the DAI score of mice at day 5 after DSS administration. (d) Quantification of histological scores of colon tissue. (e) Representative images showing H&E staining of colonic tissue in DSS-induced colitis mice. Scale bar = 100 μm. n = 5–10 mice pr group. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. DSS + PBS group by ANOVA followed by LSD post hoc test. LR: Lactobacillus rhamnosus, LP: Lactobacillus plantarum, PA: Pediococcus acidilactici, EF: Enterococcus faecium, EC: Escherichia coli